Skin cancers and precancerous lesions in Parkinson's disease patients
Identifieur interne : 000316 ( France/Analysis ); précédent : 000315; suivant : 000317Skin cancers and precancerous lesions in Parkinson's disease patients
Auteurs : Joaquim Ferreira [Portugal] ; João Maia Silva [Portugal] ; Rita Freire [Portugal] ; João Pignatelli [Portugal] ; Leonor Correia Guedes [Portugal] ; Alexandra Feij [Portugal] ; Mário Miguel Rosa [Portugal] ; Miguel Coelho [Portugal] ; João Costa [Portugal] ; Ana Noronha [Portugal] ; Russell Hewett [Portugal] ; A. Marques Gomes [Portugal] ; J. L. Cirne De Castro [Portugal] ; Olivier Rascol [France] ; Cristina Sampaio [Portugal]Source :
- Movement Disorders [ 0885-3185 ] ; 2007-07-30.
Descripteurs français
- Pascal (Inist)
- Wicri :
- topic : Homme.
English descriptors
- KwdEn :
- Aged, Case-Control Studies, Confidence Intervals, Cross-Over Studies, Female, Human, Humans, Keratosis, Male, Malignant melanoma, Middle Aged, Nervous system diseases, Odds Ratio, Parkinson Disease (physiopathology), Parkinson disease, Parkinson's disease, Precancerous Conditions (physiopathology), Questionnaires, Risk Factors, Skin Neoplasms (physiopathology), Skin cancer, Skin disease, actinic keratosis, melanoma, skin cancer.
- MESH :
- physiopathology : Parkinson Disease, Precancerous Conditions, Skin Neoplasms.
- Aged, Case-Control Studies, Confidence Intervals, Cross-Over Studies, Female, Humans, Male, Middle Aged, Odds Ratio, Questionnaires, Risk Factors.
Abstract
Our objective was to evaluate the frequency of neoplastic and preneoplastic skin lesions in Parkinson's disease (PD) patients when compared with an aged‐matched population. We performed a cross‐sectional survey in PD patients and in an age‐matched control group. Patients and controls were examined by a movement disorder specialist and a dermatologist. 150 PD patients and 146 controls were included. Thirty‐five PD patients (23.3%) presented skin lesions that could be classified as neoplastic or preneoplastic vs. 20 subjects in the control group (13.7%) (OR 95%, CI 1.92 [1.05, 3.51]). However, this difference lost statistical significance when adjusted for gender (recruitment of controls was matched just for age with an over representation of males in the PD group). Twenty‐nine PD patients (19%) presented actinic keratosis and basal cell carcinoma was diagnosed in 4 patients (3%). Although nonconclusive, our results are in agreement with previous studies suggesting an increased risk of skin cancer in PD patients. The frequency of actinic keratosis in PD patients and the associated risk to develop melanoma recommends its screening in future epidemiological studies. © 2007 Movement Disorder Society
Url:
DOI: 10.1002/mds.21575
Affiliations:
- France, Portugal
- Midi-Pyrénées
- Toulouse
- Université Toulouse III - Paul Sabatier, Université de Toulouse
Links toward previous steps (curation, corpus...)
- to stream Istex, to step Corpus: 002A41
- to stream Istex, to step Curation: 002A41
- to stream Istex, to step Checkpoint: 001683
- to stream PubMed, to step Corpus: 002695
- to stream PubMed, to step Curation: 002695
- to stream PubMed, to step Checkpoint: 002556
- to stream Ncbi, to step Merge: 001C44
- to stream Ncbi, to step Curation: 001C44
- to stream Ncbi, to step Checkpoint: 001C44
- to stream Main, to step Merge: 003A97
- to stream PascalFrancis, to step Corpus: 001587
- to stream PascalFrancis, to step Curation: 001734
- to stream PascalFrancis, to step Checkpoint: 001463
- to stream Main, to step Merge: 004053
- to stream Main, to step Curation: 002B75
- to stream Main, to step Exploration: 002B75
- to stream France, to step Extraction: 000316
Links to Exploration step
ISTEX:51643B36B6A3E14FBC303C7EA84C9BC9F9DBC7A3Le document en format XML
<record><TEI wicri:istexFullTextTei="biblStruct"><teiHeader><fileDesc><titleStmt><title xml:lang="en">Skin cancers and precancerous lesions in Parkinson's disease patients</title><author><name sortKey="Ferreira, Joaquim" sort="Ferreira, Joaquim" uniqKey="Ferreira J" first="Joaquim" last="Ferreira">Joaquim Ferreira</name></author><author><name sortKey="Silva, Joao Maia" sort="Silva, Joao Maia" uniqKey="Silva J" first="João Maia" last="Silva">João Maia Silva</name></author><author><name sortKey="Freire, Rita" sort="Freire, Rita" uniqKey="Freire R" first="Rita" last="Freire">Rita Freire</name></author><author><name sortKey="Pignatelli, Joao" sort="Pignatelli, Joao" uniqKey="Pignatelli J" first="João" last="Pignatelli">João Pignatelli</name></author><author><name sortKey="Guedes, Leonor Correia" sort="Guedes, Leonor Correia" uniqKey="Guedes L" first="Leonor Correia" last="Guedes">Leonor Correia Guedes</name></author><author><name sortKey="Feij, Alexandra" sort="Feij, Alexandra" uniqKey="Feij A" first="Alexandra" last="Feij">Alexandra Feij</name></author><author><name sortKey="Rosa, Mario Miguel" sort="Rosa, Mario Miguel" uniqKey="Rosa M" first="Mário Miguel" last="Rosa">Mário Miguel Rosa</name></author><author><name sortKey="Coelho, Miguel" sort="Coelho, Miguel" uniqKey="Coelho M" first="Miguel" last="Coelho">Miguel Coelho</name></author><author><name sortKey="Costa, Joao" sort="Costa, Joao" uniqKey="Costa J" first="João" last="Costa">João Costa</name></author><author><name sortKey="Noronha, Ana" sort="Noronha, Ana" uniqKey="Noronha A" first="Ana" last="Noronha">Ana Noronha</name></author><author><name sortKey="Hewett, Russell" sort="Hewett, Russell" uniqKey="Hewett R" first="Russell" last="Hewett">Russell Hewett</name></author><author><name sortKey="Gomes, A Marques" sort="Gomes, A Marques" uniqKey="Gomes A" first="A. Marques" last="Gomes">A. Marques Gomes</name></author><author><name sortKey="De Castro, J L Cirne" sort="De Castro, J L Cirne" uniqKey="De Castro J" first="J. L. Cirne" last="De Castro">J. L. Cirne De Castro</name></author><author><name sortKey="Rascol, Olivier" sort="Rascol, Olivier" uniqKey="Rascol O" first="Olivier" last="Rascol">Olivier Rascol</name><affiliation><country>France</country><placeName><settlement type="city">Toulouse</settlement><region type="region" nuts="2">Midi-Pyrénées</region></placeName><orgName type="university" n="3">Université Toulouse III - Paul Sabatier</orgName><orgName type="institution" wicri:auto="newGroup">Université de Toulouse</orgName></affiliation></author><author><name sortKey="Sampaio, Cristina" sort="Sampaio, Cristina" uniqKey="Sampaio C" first="Cristina" last="Sampaio">Cristina Sampaio</name></author></titleStmt><publicationStmt><idno type="wicri:source">ISTEX</idno><idno type="RBID">ISTEX:51643B36B6A3E14FBC303C7EA84C9BC9F9DBC7A3</idno><date when="2007" year="2007">2007</date><idno type="doi">10.1002/mds.21575</idno><idno type="url">https://api.istex.fr/document/51643B36B6A3E14FBC303C7EA84C9BC9F9DBC7A3/fulltext/pdf</idno><idno type="wicri:Area/Istex/Corpus">002A41</idno><idno type="wicri:Area/Istex/Curation">002A41</idno><idno type="wicri:Area/Istex/Checkpoint">001683</idno><idno type="wicri:doubleKey">0885-3185:2007:Ferreira J:skin:cancers:and</idno><idno type="wicri:source">PubMed</idno><idno type="RBID">pubmed:17516496</idno><idno type="wicri:Area/PubMed/Corpus">002695</idno><idno type="wicri:Area/PubMed/Curation">002695</idno><idno type="wicri:Area/PubMed/Checkpoint">002556</idno><idno type="wicri:Area/Ncbi/Merge">001C44</idno><idno type="wicri:Area/Ncbi/Curation">001C44</idno><idno type="wicri:Area/Ncbi/Checkpoint">001C44</idno><idno type="wicri:doubleKey">0885-3185:2007:Ferreira J:skin:cancers:and</idno><idno type="wicri:Area/Main/Merge">003A97</idno><idno type="wicri:source">INIST</idno><idno type="RBID">Pascal:07-0393269</idno><idno type="wicri:Area/PascalFrancis/Corpus">001587</idno><idno type="wicri:Area/PascalFrancis/Curation">001734</idno><idno type="wicri:Area/PascalFrancis/Checkpoint">001463</idno><idno type="wicri:doubleKey">0885-3185:2007:Ferreira J:skin:cancers:and</idno><idno type="wicri:Area/Main/Merge">004053</idno><idno type="wicri:Area/Main/Curation">002B75</idno><idno type="wicri:Area/Main/Exploration">002B75</idno><idno type="wicri:Area/France/Extraction">000316</idno></publicationStmt><sourceDesc><biblStruct><analytic><title level="a" type="main" xml:lang="en">Skin cancers and precancerous lesions in Parkinson's disease patients</title><author><name sortKey="Ferreira, Joaquim" sort="Ferreira, Joaquim" uniqKey="Ferreira J" first="Joaquim" last="Ferreira">Joaquim Ferreira</name><affiliation wicri:level="1"><country xml:lang="fr">Portugal</country><wicri:regionArea>Neurological Clinic Research Unit, Institute of Molecular Medicine, Lisbon School of Medicine, Lisbon</wicri:regionArea><wicri:noRegion>Lisbon</wicri:noRegion></affiliation></author><author><name sortKey="Silva, Joao Maia" sort="Silva, Joao Maia" uniqKey="Silva J" first="João Maia" last="Silva">João Maia Silva</name><affiliation wicri:level="1"><country xml:lang="fr">Portugal</country><wicri:regionArea>Dermatology Department, Hospital de Santa Maria, Lisbon</wicri:regionArea><wicri:noRegion>Lisbon</wicri:noRegion></affiliation></author><author><name sortKey="Freire, Rita" sort="Freire, Rita" uniqKey="Freire R" first="Rita" last="Freire">Rita Freire</name><affiliation wicri:level="1"><country xml:lang="fr">Portugal</country><wicri:regionArea>Neurological Clinic Research Unit, Institute of Molecular Medicine, Lisbon School of Medicine, Lisbon</wicri:regionArea><wicri:noRegion>Lisbon</wicri:noRegion></affiliation></author><author><name sortKey="Pignatelli, Joao" sort="Pignatelli, Joao" uniqKey="Pignatelli J" first="João" last="Pignatelli">João Pignatelli</name><affiliation wicri:level="1"><country xml:lang="fr">Portugal</country><wicri:regionArea>Dermatology Department, Hospital de Santa Maria, Lisbon</wicri:regionArea><wicri:noRegion>Lisbon</wicri:noRegion></affiliation></author><author><name sortKey="Guedes, Leonor Correia" sort="Guedes, Leonor Correia" uniqKey="Guedes L" first="Leonor Correia" last="Guedes">Leonor Correia Guedes</name><affiliation wicri:level="1"><country xml:lang="fr">Portugal</country><wicri:regionArea>Neurological Clinic Research Unit, Institute of Molecular Medicine, Lisbon School of Medicine, Lisbon</wicri:regionArea><wicri:noRegion>Lisbon</wicri:noRegion></affiliation></author><author><name sortKey="Feij, Alexandra" sort="Feij, Alexandra" uniqKey="Feij A" first="Alexandra" last="Feij">Alexandra Feij</name><affiliation wicri:level="1"><country xml:lang="fr">Portugal</country><wicri:regionArea>Dermatology Department, Hospital de Santa Maria, Lisbon</wicri:regionArea><wicri:noRegion>Lisbon</wicri:noRegion></affiliation></author><author><name sortKey="Rosa, Mario Miguel" sort="Rosa, Mario Miguel" uniqKey="Rosa M" first="Mário Miguel" last="Rosa">Mário Miguel Rosa</name><affiliation wicri:level="1"><country xml:lang="fr">Portugal</country><wicri:regionArea>Neurological Clinic Research Unit, Institute of Molecular Medicine, Lisbon School of Medicine, Lisbon</wicri:regionArea><wicri:noRegion>Lisbon</wicri:noRegion></affiliation></author><author><name sortKey="Coelho, Miguel" sort="Coelho, Miguel" uniqKey="Coelho M" first="Miguel" last="Coelho">Miguel Coelho</name><affiliation wicri:level="1"><country xml:lang="fr">Portugal</country><wicri:regionArea>Neurological Clinic Research Unit, Institute of Molecular Medicine, Lisbon School of Medicine, Lisbon</wicri:regionArea><wicri:noRegion>Lisbon</wicri:noRegion></affiliation></author><author><name sortKey="Costa, Joao" sort="Costa, Joao" uniqKey="Costa J" first="João" last="Costa">João Costa</name><affiliation wicri:level="1"><country xml:lang="fr">Portugal</country><wicri:regionArea>Neurological Clinic Research Unit, Institute of Molecular Medicine, Lisbon School of Medicine, Lisbon</wicri:regionArea><wicri:noRegion>Lisbon</wicri:noRegion></affiliation></author><author><name sortKey="Noronha, Ana" sort="Noronha, Ana" uniqKey="Noronha A" first="Ana" last="Noronha">Ana Noronha</name><affiliation wicri:level="1"><country xml:lang="fr">Portugal</country><wicri:regionArea>Neurological Clinic Research Unit, Institute of Molecular Medicine, Lisbon School of Medicine, Lisbon</wicri:regionArea><wicri:noRegion>Lisbon</wicri:noRegion></affiliation></author><author><name sortKey="Hewett, Russell" sort="Hewett, Russell" uniqKey="Hewett R" first="Russell" last="Hewett">Russell Hewett</name><affiliation wicri:level="1"><country xml:lang="fr">Portugal</country><wicri:regionArea>Neurological Clinic Research Unit, Institute of Molecular Medicine, Lisbon School of Medicine, Lisbon</wicri:regionArea><wicri:noRegion>Lisbon</wicri:noRegion></affiliation></author><author><name sortKey="Gomes, A Marques" sort="Gomes, A Marques" uniqKey="Gomes A" first="A. Marques" last="Gomes">A. Marques Gomes</name><affiliation wicri:level="1"><country xml:lang="fr">Portugal</country><wicri:regionArea>Dermatology Department, Hospital de Santa Maria, Lisbon</wicri:regionArea><wicri:noRegion>Lisbon</wicri:noRegion></affiliation></author><author><name sortKey="De Castro, J L Cirne" sort="De Castro, J L Cirne" uniqKey="De Castro J" first="J. L. Cirne" last="De Castro">J. L. Cirne De Castro</name><affiliation wicri:level="1"><country xml:lang="fr">Portugal</country><wicri:regionArea>Dermatology Department, Hospital de Santa Maria, Lisbon</wicri:regionArea><wicri:noRegion>Lisbon</wicri:noRegion></affiliation></author><author><name sortKey="Rascol, Olivier" sort="Rascol, Olivier" uniqKey="Rascol O" first="Olivier" last="Rascol">Olivier Rascol</name><affiliation wicri:level="1"><country xml:lang="fr">France</country><wicri:regionArea>Clinical Investigation Centre, Department of Clinical Pharmacology and Neurosciences, University Hospital, Toulouse</wicri:regionArea><placeName><settlement type="city">Toulouse</settlement></placeName><placeName><settlement type="city">Toulouse</settlement><region type="region" nuts="2">Midi-Pyrénées</region></placeName><orgName type="university" n="3">Université Toulouse III - Paul Sabatier</orgName><orgName type="institution" wicri:auto="newGroup">Université de Toulouse</orgName></affiliation></author><author><name sortKey="Sampaio, Cristina" sort="Sampaio, Cristina" uniqKey="Sampaio C" first="Cristina" last="Sampaio">Cristina Sampaio</name><affiliation wicri:level="1"><country xml:lang="fr">Portugal</country><wicri:regionArea>Neurological Clinic Research Unit, Institute of Molecular Medicine, Lisbon School of Medicine, Lisbon</wicri:regionArea><wicri:noRegion>Lisbon</wicri:noRegion></affiliation></author></analytic><monogr></monogr><series><title level="j">Movement Disorders</title><title level="j" type="sub">Official Journal of the Movement Disorder Society</title><title level="j" type="abbrev">Mov. Disord.</title><idno type="ISSN">0885-3185</idno><idno type="eISSN">1531-8257</idno><imprint><publisher>Wiley Subscription Services, Inc., A Wiley Company</publisher><pubPlace>Hoboken</pubPlace><date type="published" when="2007-07-30">2007-07-30</date><biblScope unit="vol">22</biblScope><biblScope unit="issue">10</biblScope><biblScope unit="page" from="1471">1471</biblScope><biblScope unit="page" to="1475">1475</biblScope></imprint><idno type="ISSN">0885-3185</idno></series><idno type="istex">51643B36B6A3E14FBC303C7EA84C9BC9F9DBC7A3</idno><idno type="DOI">10.1002/mds.21575</idno><idno type="ArticleID">MDS21575</idno></biblStruct></sourceDesc><seriesStmt><idno type="ISSN">0885-3185</idno></seriesStmt></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Aged</term><term>Case-Control Studies</term><term>Confidence Intervals</term><term>Cross-Over Studies</term><term>Female</term><term>Human</term><term>Humans</term><term>Keratosis</term><term>Male</term><term>Malignant melanoma</term><term>Middle Aged</term><term>Nervous system diseases</term><term>Odds Ratio</term><term>Parkinson Disease (physiopathology)</term><term>Parkinson disease</term><term>Parkinson's disease</term><term>Precancerous Conditions (physiopathology)</term><term>Questionnaires</term><term>Risk Factors</term><term>Skin Neoplasms (physiopathology)</term><term>Skin cancer</term><term>Skin disease</term><term>actinic keratosis</term><term>melanoma</term><term>skin cancer</term></keywords><keywords scheme="MESH" qualifier="physiopathology" xml:lang="en"><term>Parkinson Disease</term><term>Precancerous Conditions</term><term>Skin Neoplasms</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Aged</term><term>Case-Control Studies</term><term>Confidence Intervals</term><term>Cross-Over Studies</term><term>Female</term><term>Humans</term><term>Male</term><term>Middle Aged</term><term>Odds Ratio</term><term>Questionnaires</term><term>Risk Factors</term></keywords><keywords scheme="Pascal" xml:lang="fr"><term>Cancer de la peau</term><term>Homme</term><term>Kératose</term><term>Mélanome malin</term><term>Parkinson maladie</term><term>Peau pathologie</term><term>Système nerveux pathologie</term></keywords><keywords scheme="Wicri" type="topic" xml:lang="fr"><term>Homme</term></keywords></textClass><langUsage><language ident="en">en</language></langUsage></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">Our objective was to evaluate the frequency of neoplastic and preneoplastic skin lesions in Parkinson's disease (PD) patients when compared with an aged‐matched population. We performed a cross‐sectional survey in PD patients and in an age‐matched control group. Patients and controls were examined by a movement disorder specialist and a dermatologist. 150 PD patients and 146 controls were included. Thirty‐five PD patients (23.3%) presented skin lesions that could be classified as neoplastic or preneoplastic vs. 20 subjects in the control group (13.7%) (OR 95%, CI 1.92 [1.05, 3.51]). However, this difference lost statistical significance when adjusted for gender (recruitment of controls was matched just for age with an over representation of males in the PD group). Twenty‐nine PD patients (19%) presented actinic keratosis and basal cell carcinoma was diagnosed in 4 patients (3%). Although nonconclusive, our results are in agreement with previous studies suggesting an increased risk of skin cancer in PD patients. The frequency of actinic keratosis in PD patients and the associated risk to develop melanoma recommends its screening in future epidemiological studies. © 2007 Movement Disorder Society</div></front></TEI><affiliations><list><country><li>France</li><li>Portugal</li></country><region><li>Midi-Pyrénées</li></region><settlement><li>Toulouse</li></settlement><orgName><li>Université Toulouse III - Paul Sabatier</li><li>Université de Toulouse</li></orgName></list><tree><country name="Portugal"><noRegion><name sortKey="Ferreira, Joaquim" sort="Ferreira, Joaquim" uniqKey="Ferreira J" first="Joaquim" last="Ferreira">Joaquim Ferreira</name></noRegion><name sortKey="Coelho, Miguel" sort="Coelho, Miguel" uniqKey="Coelho M" first="Miguel" last="Coelho">Miguel Coelho</name><name sortKey="Costa, Joao" sort="Costa, Joao" uniqKey="Costa J" first="João" last="Costa">João Costa</name><name sortKey="De Castro, J L Cirne" sort="De Castro, J L Cirne" uniqKey="De Castro J" first="J. L. Cirne" last="De Castro">J. L. Cirne De Castro</name><name sortKey="Feij, Alexandra" sort="Feij, Alexandra" uniqKey="Feij A" first="Alexandra" last="Feij">Alexandra Feij</name><name sortKey="Freire, Rita" sort="Freire, Rita" uniqKey="Freire R" first="Rita" last="Freire">Rita Freire</name><name sortKey="Gomes, A Marques" sort="Gomes, A Marques" uniqKey="Gomes A" first="A. Marques" last="Gomes">A. Marques Gomes</name><name sortKey="Guedes, Leonor Correia" sort="Guedes, Leonor Correia" uniqKey="Guedes L" first="Leonor Correia" last="Guedes">Leonor Correia Guedes</name><name sortKey="Hewett, Russell" sort="Hewett, Russell" uniqKey="Hewett R" first="Russell" last="Hewett">Russell Hewett</name><name sortKey="Noronha, Ana" sort="Noronha, Ana" uniqKey="Noronha A" first="Ana" last="Noronha">Ana Noronha</name><name sortKey="Pignatelli, Joao" sort="Pignatelli, Joao" uniqKey="Pignatelli J" first="João" last="Pignatelli">João Pignatelli</name><name sortKey="Rosa, Mario Miguel" sort="Rosa, Mario Miguel" uniqKey="Rosa M" first="Mário Miguel" last="Rosa">Mário Miguel Rosa</name><name sortKey="Sampaio, Cristina" sort="Sampaio, Cristina" uniqKey="Sampaio C" first="Cristina" last="Sampaio">Cristina Sampaio</name><name sortKey="Silva, Joao Maia" sort="Silva, Joao Maia" uniqKey="Silva J" first="João Maia" last="Silva">João Maia Silva</name></country><country name="France"><noRegion><name sortKey="Rascol, Olivier" sort="Rascol, Olivier" uniqKey="Rascol O" first="Olivier" last="Rascol">Olivier Rascol</name></noRegion></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Wicri/Santé/explor/MovDisordV3/Data/France/Analysis
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 000316 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/France/Analysis/biblio.hfd -nk 000316 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien
|wiki= Wicri/Santé
|area= MovDisordV3
|flux= France
|étape= Analysis
|type= RBID
|clé= ISTEX:51643B36B6A3E14FBC303C7EA84C9BC9F9DBC7A3
|texte= Skin cancers and precancerous lesions in Parkinson's disease patients
}}
| This area was generated with Dilib version V0.6.23. |  |